Join the St. Louis Rams this Saturday to be a part of cancer history

Wordpress_CPS3ad_blktextSt. Louis Rams Running Back Chase Reynolds, and his wife Kila, are encouraging St. Louisans to join their Rams family for a ground-breaking research effort this Saturday. Individuals can come to Rams Park in Earth City, First Baptist Church of Arnold, or Mineral Area College in Park Hills to join them in Cancer Prevention Study-3.

The American Cancer Society is specifically looking for individuals between the ages of 30-65 who have never been diagnosed with cancer and who are willing to make an easy, but long-term commitment to the study. Research will continue to reveal what causes and what prevents cancer.

In approximately 20 minutes time, individuals will take a survey, have their waist measured, and give a small blood sample similar to what is taken at a doctor’s office. Then every two years or so, a new survey will be mailed to them for follow-up.

You can change the face of cancer for future generations. Join us on Saturday, and learn more at http://www.cancerstudymo.org.

CPS-3 Enrollment in Jefferson City Exceeds Expectations

Craig Boring presents a plaque to the Goldschmidt Cancer Center for hosting the three-day enrollment for CPS-3

An amazing partnership with Capital Region Medical Center’s Goldschmidt Cancer Center and the American Cancer Society shattered expectations last week enrolling 374 participants into the Cancer Prevention Study-3. More than 40 people walked in without an appointment over the three days of enrollment in Jefferson City, Mo., proving that word of mouth increases participation.

CPS-3 is a grassroots effort where local communities from across the country can support cancer research by participating actively in this historic research study. The goal of CPS-3 is to better understand the factors (lifestyle, environmental, genetic) that cause or prevent cancer and, ultimately, to help eliminate cancer as a major health concern for future generations.

Many thanks to the staff of Goldschmidt Cancer Center for opening their doors, to the volunteer planning committee and CPS-3 Champions for all of their hard with planning and recruitment, and to our Society staff for executing a successful event.

Follow us for information on future enrollment sites in Missouri or visit http://cps3.mo.org/.

American Cancer Society Awards New Grant to Saint Louis University Researcher

New American Cancer Society-funded researcher, Dr. Richard DiPaolo of Saint Louis University.

Since 1946, the American Cancer Society has invested more than $3.6 billion to fund researchers in their work to help discover causes, treatments, prevention and early detection methods for cancer. Today, the American Cancer Society announced numerous new grants nationwide to help find cures and fight back. One of the newest grants is awarded to Saint Louis University’s Richard DiPaolo, PhD., of the molecular microbiology and immunology department. The grant of $720,000 will help research the regulation of gastric cancer in a model of autoimmune gastritis. “I believe my research project addresses important questions that will advance our understanding of inflammation and cancer,” says DiPaolo. 

Another local grant of $40,000 has been renewed for Sarah Bollinger of Washington University. Sarah’s research is focused in young African-American women with triple-negative breast cancer. This brings the total funding from the American Cancer Society to 16 grants in St. Louis at $8,275,000.

DiPaolo has studied inflammation in the stomach and how to reduce it and in turn reduce the risk of developing cancer. He has found that injecting a modified version of a specific type of cell known as a “T regulatory cell” can suppress inflammation in the stomach. This inflammation can be caused by certain kinds of diseases, such asgastritis or colitis. DiPaolo now hopes that with support from this grant he will be able “to determine whether injecting modified T regulatory cells during early, intermediate, and late stages of disease is an effective means to prevent stomach cancer.” 

DiPaolo has also collaborated with Jason Mills, PhD., of Washington University, who is also a current American Cancer Society funded researcher. Their combined expertise gave them an advantage and a unique look at how most gastric cancers are adenocarcinomas, cancers that begin in cells lining internal organs. Working together, they also found how the immune system regulates certain cells during the progression of this type of cancer.

Bollinger’s research will focus on the link between developing the specific subtype of breast cancer and psychosocial factors. She also wants to increase understanding of the population of women diagnosed with this disease and in turn be able to provide more holistic care.

The American Cancer Society’s goal is to eliminate cancer as a major health problem, and this is exactly what these researchers work towards with help from their grants. “Without the support of the American Cancer Society it would be difficult if not impossible to come up with the resources to complete this project,” Dipaolo says. This grant will help him continue his research and understanding of these cells and inflammation in regards to early detection as well as prevention of cancer. “I believe that a better understanding of the immune system and how to manipulate its activity will lead to new treatments and cures for many diseases in the future, including cancers,” Dipaolo says. 

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